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KMID : 0982820100090020106
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Journal of Lung Cancer
2010 Volume.9 No. 2 p.106 ~ p.109
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Tumor Lysis Syndrome Induced by Radiotherapy in Non- Small Cell Lung Cancer
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Noh Dong-Hyo
Hwang Ki-Eun
Shin Jeong-Hyun
Kim Dong
Cho Kyung-Hwa
Jeong Eun-Taik
Kim Hak-Ryul
Choi Keum-Ha
Park Seong-Hoon
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Abstract
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Tumor lysis syndrome (TLS) is an oncologic emergency that is characterized by numerous metabolic abnormalities, including hyperuricemic nephropathy, hyperphosphatemia, hypocalcemia, hyperkalemia and increased serum creatinine. This syndrome is common for tumors with rapid cell turnover and growth rates, and for bulky tumors with high sensitivity to anti-neoplastic treatments. Hence, TLS is a well-recognized clinical problem in hematologic malignancies. TLS is rarely observed to be induced in solid tumors by chemotherapy. Herein we present the second case of TLS that developed during radiotherapy in a patient with non-small cell lung cancer.
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KEYWORD
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Tumor lysis syndrome, Radiotherapy, Non-small cell lung carcinoma
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